My Projects

 To the question  Could Spring batch be the model describing how Crispr cas9 works ? Gemini answered  Spring Batch as a Model for CRISPR-Cas9: A Thought Experiment Yes, Spring Batch could potentially serve as a conceptual model for understanding how CRISPR-Cas9 works. Here's a breakdown of how the two might align: Spring Batch Components and CRISPR-Cas9: Job:  The overall CRISPR-Cas9 process, including target identification, guide RNA design, and gene editing. Step:  Individual stages of the process, such as target recognition, cleavage, and repair. Reader:   The guide RNA, which reads the target DNA sequence.     Processor:   The Cas9 enzyme, which processes the target DNA by cutting it at specific locations.     Writer:  The cell's repair machinery, which writes the new DNA sequence. Similarities and Differences: Sequencing:  Both Spring Batch and CRISPR-Cas9 involve a sequential process.  In Spring Batch, this is often a batch job processing data in chunks.  In CRISPR-Cas9,

I share with you email received from Embl-Ebi about my IT model  https://thecrisprcas9model.blogspot.com/2024/02/generative-ai-explaining-my-model.html?m=1 Dear Wadi, I recommend you talk to computational biologists locally to write this up as a manuscript and submit it to a peer-reviewed journal. Hopefullyou should get feedback to improve your manuscript. For example you coud reach out to these authors Designing and running an advanced Bioinformatics and genome analyses course in Tunisia - PubMed nlm.nih.gov I am sure, you could find many more bioinformatician from Tunisia, just search for papers in PubMed and collaborate with them. Hopefully you will find some one to help you with writing this mansucript. Best regards Sheriff Please share in order To help me find Tunisian bioinformatician To write a manuscript

  I have a problem to learn chinese. I found it difficult but I asked myself : Chinese people find learning Arabic, English, French, Deutsch etc. difficult too. So I decided to find a solution for beginners to learn languages. The new way The new method is based on learning by Keyboard and text to Speech and ChatGPT.  The teacher (ChatGPT) shows a letter to his pupils and read it twice and then asks his students to find it on the keyboard and they should press the corrspondent key and hit the baffle. Then they compare the sound response of text to Speech with what the teacher (ChatGPT) taught them. Step by Step, letter by letter and word by Word and then small sentences the students will learn the basics of the languages essentially how to read. A course of writing must be taken in parallel with what they read. You can try the protoype App without Teacher (ChatGPT) at This Following link   https://didipostman.github.io/ I look forward for your replies comments and feedbacks -- Minds, l

  To the question : " Could Spring batch be the model describing how Crispr cas9 works" ChatGPT answered : " No, Spring Batch is a framework for developing and executing batch applications in the Java platform, while CRISPR-Cas9 is a genome editing tool that allows for targeted modification of DNA sequences. They are not related and cannot be used to describe the mechanism of CRISPR-Cas9." To the question :" Spring batch + karp rabin could be a model for dna damage repair" ChatGPT answered : " No, Spring Batch and the Karp-Rabin algorithm are not a model for DNA damage repair. Spring Batch is a software framework for batch processing, while the Karp-Rabin algorithm is a string matching algorithm. DNA damage repair is a complex biological process that involves multiple molecular mechanisms, including DNA damage recognition, signaling, and repair. These mechanisms cannot be described or modeled using a software framework or a string matching algorithm.&

 To the question : " Could Spring batch be the model describing how Crispr cas9 works ?!" Gemini answered There is an interesting proposal suggesting Spring Batch, a Java framework for batch processing, could be used as a conceptual model to describe CRISPR-Cas9 functionality. While not a completely accurate representation of the biological process, it serves as an intriguing analogy. Here's a breakdown of the comparison: Spring Batch Components: ItemReader:  Reads input data,  analogous to CRISPR guide RNA identifying the target DNA sequence. ItemProcessor:  Processes the data,  similar to Cas9 protein binding to the target sequence. ItemWriter:  Writes the processed data,  comparable to Cas9 cutting the DNA at the identified location. CRISPR-Cas9 Components: Guide RNA:  Short RNA sequence guiding Cas9 to the target location. Cas9 protein:  Enzyme that cuts DNA at the specified location. Repair mechanisms:  Cellular processes that repair the cut DNA,  leading to var