My Projects

 To the question : " Could Spring batch be the model describing how Crispr cas9 works ?!" Gemini answered There is an interesting proposal suggesting Spring Batch, a Java framework for batch processing, could be used as a conceptual model to describe CRISPR-Cas9 functionality. While not a completely accurate representation of the biological process, it serves as an intriguing analogy. Here's a breakdown of the comparison: Spring Batch Components: ItemReader:  Reads input data,  analogous to CRISPR guide RNA identifying the target DNA sequence. ItemProcessor:  Processes the data,  similar to Cas9 protein binding to the target sequence. ItemWriter:  Writes the processed data,  comparable to Cas9 cutting the DNA at the identified location. CRISPR-Cas9 Components: Guide RNA:  Short RNA sequence guiding Cas9 to the target location. Cas9 protein:  Enzyme that cuts DNA at the specified location. Repair mechanisms:  Cellular processes that ...

 "Spring batch for sequencing DNA  A computational model for DNA damage repair which could explain how CRISPR Cas9 Works" is  available on Zenodo https://zenodo.org/records/8424872 I look forward for your replies comments and feedbacks -- Minds, like parachutes, function best when open. ,,,                       (o o)  / --------oOO--(_)--OOo--------------------\  | Wadï Mami didipostman  | Github :  https://www.github.com/didipostman  | e-mail : wmami@steg.com.tn / didipostman77@gmail.com  |  Twitter : @MamiWad3 | \----------------------------------------/                           | |  | \---------------/ \------------------------/

Today marks my last call since 2012 I didn't give up sharing in blog posts, articles (Academia.edu, ResearchGate.net), Tweets, FaceBook, LinkedIn, Reddit etc Forgive me for insisting, the idea is haunting me since 2012 and I contacted many people but no one answered me. I had a flash since I saw the sequence diagram that explains how Spring Batch works. I share with you my DNA sequencing idea with Spring batch which could be a computational model for DNA damage repair and may could explain how CRISPR Cas9 works. Please visit https://didipostmanprojects.blogspot.com/2023/10/my-article-now-on-google.html In fact I can't go further with my idea, you you can. My idea is under Mit License . THANKS The sequence diagram is useful for something I don't know how but I have got some strange feeling when I have seen it since 2012. Maybe you find the idea useful interesting and continue dev. I look forward for your replies comments and feedbacks -- Minds, like parachutes, function best...

  Spring Batch for sequencing DNA A computational model for DNA damage repair and could explain how CRISPR Cas9 works Author : Wadï Mami E-mail : wmami@steg.com.tn / didipostman77@gmail.com Date : 09/10/2023 Spring Batch reads and process DNA sequentially until reaching commit-interval value then it writes transformed items (DNA) simultaneously . Below is a code representation of the same concepts shown above: List items = new Arraylist(); for ( int i = 0 ; i < commitInterval; i++){     Object item = itemReader.read()     Object processedItem = itemProcessor.process(item);     items.add(processedItem); } itemWriter.write(items); In my template I used a DNASequence_Processor class that implements itemProcessor and use Karp Rabin Algorithm. ( You can use any other algorithm of pattern recognition instead) Here my repository : https://github.com/didipostman/CrisprCas9/ And here path to ...